Rating the very best glucosamine dietary supplements of 2022

Glucosamine performs an necessary position in preserving joint well being. Glucosamine reduces joint irritation and ache from arthritis, and will assist rebuild broken cartilage and gradual the progressive lack of joint area that happens within the illness.

Many individuals discover that glucosamine is useful for different kinds of joint ache as nicely, akin to sports activities accidents.

Want a glucosamine complement to alleviate your joint ache? Don’t fear, our analysis staff has you lined.

Listed here are the very best glucosamine dietary supplements accessible proper now.

Why You Ought to Belief Us

    Our advisory panel and our analysis staff rank the very best well being merchandise and dietary supplements primarily based on efficiency, label accuracy, and the efficacy of the substances within the merchandise.


Final up to date: September 2, 2022
Glucosamine dietary supplements thought of: 25
Hours of analysis: 37
Specialists reviewed: 8
Scientific papers referenced: 12


Greatest Total

1. Stay Aware MoveWell Glucosamine

  • Is a simple choose for joint ache
  • Fights irritation, scale back ache, and encourage therapeutic in connective tissue
  • Promotes mobility and adaptability by serving to direct collagen to the joints
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Greatest with hyaluronic acid

2. Important Components Glucosamine Chondroitin

  • Helps to scale back joint irritation and enhance the formation of recent cartilage
  • Comes with substances that fight soreness and discomfort to advertise higher mobility
  • Improves long run well being for joints
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Greatest with MSM

3. Kirkland Signature Glucosamine With MSM

  • Gives easy and environment friendly dietary supplements that tackle your primary wants
  • 750 mg of glucosamine in every pill
  • Has a strong anti-inflammatory impact
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  • Delivers 1000 mg of glucosamine hydrochloride per pill
  • Helps and promote joint well being
  • Accommodates hyaluronic acid that help cartilage regeneration properties of glucosamine
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Greatest for irritation

5. Phytochoice Glucosamine Chondroitin

  • It delivers a stability of assorted substances to assist with joint ache
  • Every pill accommodates solely 500 mg of glucosamine
  • Strengthens cartilage
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6. Made in Utah Glucosamine Chondroitin Turmeric MSM

  • A barely larger high quality complement with this joint assist product
  • 500 mg of glucosamine per pill
  • Has an anti-inflammatory and ache relieving energy within the complement
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7. Zenwise Superior Power Joint Help

  • Greatest relating to all-around joint regeneration
  • Promotes higher joint mobility for individuals who have an lively life-style
  • Advance method that promote energy and adaptability for the joints
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8. USA Nutra Most Power Glucosamine Chondroitin Turmeric MSM

  • Multi-ingredient complement centered on joint well being
  • 500 mg of glucosamine per pill
  • Helps Irritation
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9. Physician’s Greatest Glucosamine Chondroitin MSM

  • Delivers 1500 mg of glucosamine
  • Helps and helps joints and maintains wholesome pores and skin, nails, and hair
  • Gluten free, Soy free, and Non-GMO
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10. Vitabreeze Glucosamine Chondroitin MSM & Turmeric

  • Multi-ingredient joint assist complement
  • Vegetarian Complement that’s Non-GMO, gluten free and soy free
  • Very straightforward to swallow capsules
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11. BlueBonnet Glucosamine Chondroitin Plus MSM

  • Has high-quality and high-purity dietary supplements
  • Low glucosamine content material per pill
  • Soy-free, gluten-free and dairy-free
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1. Stay Aware MoveWell Glucosamine

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MoveWell helps and protects your joints by sustaining cartilage, lubricating joints, and enhance glutathione manufacturing to combat irritation.

It accomplishes this via a number of clinically backed substances, together with 600mg of chondroitin, 600mg of MSM, 1500mg of glucosamine, 100mg of AprèsFlex® Boswellia, 100mg of curcumin and 100mg of hyaluronic acid per serving.

MoveWell is freed from inflammatory brokers, together with gluten, soy, dairy, and sugar. Additionally it is manufactured in a GMP-certified facility within the USA.

For the very best joint assist method, MoveWell glucosamine is the very best on the market.

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2. Important Components Glucosamine Chondroitin

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Important Components Glucosamine Chondroitin helps to scale back joint irritation and enhance the formation of recent cartilage.

It combines hyaluronic acid, curcumin and MSM with glucosamine and chondroitin to offer a few of the finest joint aid available on the market.

Made within the USA and third get together examined, it’s a wonderful choice.

3. Kirkland Signature Glucosamine

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Kirkland Signature offers a strong dosage of glucosamine per pill, and contains MSM as nicely, one other fashionable joint complement that fights irritation and ache.

The capsules have a bit extra binders and fillers than you’ll discover in our prime picks, however the dosage nonetheless makes it a strong choose.

4. Made in Utah Glucosamine

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Made in Utah has a strong 500 mg of glucosamine per pill, together with chondroitin, turmeric, and MSM plus a number of much less frequent extras. Boswellia extract, quercetin, and methionine all add to its pain-relieving energy.

5. Schiff Glucosamine

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Schiff’s glucosamine formulation delivers 1000 mg of glucosamine hydrochloride per pill, together with 1.6 mg of hyaluronic acid, which assists with cartilage regeneration.

The excessive dose is nice, however purists received’t just like the components, emulsifiers, and coloring brokers included within the capsule.

6. Zenwise Joint Help

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Zenwise is among the many finest relating to all-around joint regeneration. Its glucosamine content material (500 mg) is center of the street, however you’ll additionally discover the natural extracts like boswellia and curcumin, which may be robust to search out within the competitors.

7. Phytochoice Glucosamine Chondroitin

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Phytochoice delivers a stability of glucosamine, chondroitin, quercetin, turmeric, and boswellia extract, so it’s a reasonably versatile choice. Nevertheless, the uncooked dosage of glucosamine isn’t nearly as good, which hurts its place within the rankings a bit. 

8. USA Nutra Most Power Glucosamine

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USA Nutra’s tackle glucosamine is fairly good, with 500 mg of glucosamine per pill, in addition to the namesake extras and quercetin and methionine for good measure.

The shortage of additional filler compound is interesting to individuals who wish to hold the components of their complement to a minimal.

9. Physician’s Greatest Glucosamine Chondroitin MSM

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Physician’s Greatest makes a glucosamine complement filled with glucosamine, chondroitin, and a specialised type of MSM. The one draw back? The per-capsule dosage isn’t so sizzling, touchdown it additional down within the rankings.

10. BlueBonnet Glucosamine Chondroitin

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BlueBonnet delivers a easy, efficient glucosamine complement whose solely weak point is a reasonably low dose per capsule. The complement design is nice, but it surely simply doesn’t match as much as the competitors relating to dosage.

Class winners

Greatest glucosamine total: Stay Aware MoveWell Glucosamine

MoveWell contains glucosamine alongside an astounding 5 different biologically lively compounds to combat irritation, scale back ache, and encourage therapeutic in connective tissue. Due to this breadth of substances, it’s our prime advice.

Greatest glucosamine for irritation: Important Components Glucosamine Chondroitin

Important Components contains a number of all-natural substances to help with glucosamine’s anti-inflammatory properties. These embrace chondroitin, hyaluronic acid,  and boswellia extract—all of that are nice for reducing again on irritation in your physique.

Greatest glucosamine for joint ache: Stay Aware MoveWell Glucosamine

With joint-nourishing compounds like hyaluronic acid and chondroitin, plus boswellia and curcumin to chop down on irritation, MoveWell is a simple choose for joint ache. 

Greatest glucosamine with MSM: Kirkland Signature Glucosamine MSM

If you wish to mix the cartilage-soothing results of glucosamine with the highly effective anti-inflammatory results of MSM, Kirkland is the best way to go. With 750 mg of every, it’s our prime choose for MSM/glucosamine combos. 

Greatest glucosamine for knees: Stay Aware MoveWell Glucosamine

The knee is likely one of the most typical places of arthritis and damage, as a result of excessive forces it must bear throughout strolling and different actions. MoveWell is a superb alternative for folks with knee ache, as a result of it accommodates compounds that fight irritation that happens in response to broken tissue within the knees, and it contains compounds that encourage therapeutic of connective tissue as nicely. 

Greatest glucosamine with hyaluronic acid: Stay Aware MoveWell Glucosamine

Stay Aware delivers glucosamine alongside 100 mg of hyaluronic acid, which is famend for its potential to lubricate joint surfaces. The centered formulation of this complement makes it nice for individuals who wish to benefit from hyaluronic acid’s mobility-enhancing properties. 

Who can buy glucosamine?

Glucosamine is likely one of the hottest and simplest joint dietary supplements for lowering irritation, treating joint ache, and slowing down or doubtlessly even reversing harm to cartilage. It’s an awesome complement for:

Individuals with painful knees, hips, or different joints. Glucosamine can’t work miracles, however many individuals discover that it considerably reduces joint ache, and medical analysis backs up its potential to decelerate goal markers of joint harm.

Individuals with osteoarthritis. Many of the analysis supporting using glucosamine focuses on osteoarthritis, which causes harm, degeneration, and irritation, suggesting this can be a nice use-case for glucosamine.  

Individuals with sports activities accidents to their joints. Glucosamine can do extra than simply assist arthritis: some analysis signifies it’s a helpful option to scale back ache from sports activities accidents, like outdated knee or ankle sprains that by no means absolutely healed.

How we ranked

Since glucosamine is so well-studied within the scientific literature, we used the very best medical analysis to information our choice of glucosamine dietary supplements, primarily based on the next standards: 

Efficient dosageWe appeared for dosages and formulations that lined up nicely with scientific research —that meant dietary supplements that make it straightforward to take what seems to be the optimum dosage for glucosamine, which is at the least 1500 mg of glucosamine per day.

A deal with delivering pure glucosamine. Not like our rankings of general-purpose joint dietary supplements, we put much less emphasis on the inclusion of different doubtlessly biologically lively compounds like MSM or hyaluronic acid when evaluating the standard of a glucosamine complement.

Whereas further substances had been a small perk that boosted the scores of some glucosamine dietary supplements in our rankings, our main focus was dosage and purity.

No binders, fillers, or synthetic components. We dropped dietary supplements from consideration in the event that they contained an excessive amount of in the best way of binders and fillers.

Since glucosamine is already derived from animal merchandise (shellfish, normally), it didn’t matter to our analysis staff whether or not the complement was delivered in a cellulose or gelatin capsule.

The highest performers had been merchandise that successfully delivered a excessive dose of glucosamine whereas preserving additional substances to a minimal.

If you’re in search of a glucosamine complement that gives the identical advantages seen in essentially the most profitable scientific analysis, you’ll discover it in our rankings.


Glucosamine helps scale back irritation and joint ache. It fights ache by by encouraging cartilage to soak up extra water, preserving the cartilage hydrated (1,2).

Glucosamine may additionally enhance the synthesis of cartilage tissue. Analysis on older adults with arthritis signifies that glucosamine can gradual or halt the development of joint harm in arthritis (3,4).

Glucosamine upregulates synthesis of the constructing blocks of cartilage. In accordance with a examine printed by researchers in Italy, glucosamine sulfate will increase the synthesis of a kind of protein known as proteoglycan, which make up a big quantity of the mass in cartilage (5).

Glucosamine might assist scale back ache from outdated sports activities accidents. A examine on folks with injury-related, non-arthritic knee ache skilled important enhancements in ache after taking 2000 mg of glucosamine for twelve weeks (6).

Glucosamine works higher for joint ache than again ache. In distinction to the above outcomes on knee and hip ache, analysis from Norway suggests glucosamine isn’t as useful when you could have continual low again ache (7).

Unwanted effects

Analysis exhibits glucosamine is protected and well-tolerated by nearly everybody. Scientific trials haven’t discovered any important distinction within the charge of negative effects in glucosamine versus placebo.

Glucosamine is derived from shellfish, so it might set off shellfish allergy symptoms. The one potential hostile impact to pay attention to is the truth that glucosamine is derived from marine shells, so anybody with a extreme shellfish allergy ought to keep away from glucosamine dietary supplements.

Really useful dosage

Greatest outcomes come from round 1500 mg per day. That quantity comes from a examine that examined doses from 750 to 3000 mg per day (8).

Above 1500 mg per day your physique can’t soak up any extra glucosamine. Larger doses are nonetheless protected, however don’t present any further advantages by way of bioavailability.


Q: Why would you’re taking glucosamine?

A: Glucosamine is hottest as a complement for joint ache that’s linked to osteoarthritis, and that is the appliance that’s most well-supported by scientific analysis.

Nevertheless, it’s additionally logical to take glucosamine for different joint ache, like knee ache from an acute sports activities damage, or ache and irritation from outdated joint accidents that by no means absolutely went away.

Q: Is glucosamine good on your joints?

A: Glucosamine has been studied closely as a manner to enhance joint well being and gradual and even doubtlessly reverse the degenerative progress of osteoarthritis, the place cartilage is progressively broken and infected over time, resulting in ache and incapacity.

Whereas glucosamine can’t work miracles, it does lower down on a few of the ache and limitations to your regular every day routine that may be attributable to joint harm and illness.

Q: Do any joint dietary supplements actually work?

A: The most effective scientific analysis helps small however important advantages from joint dietary supplements primarily based on glucosamine, chondroitin, and MSM as nicely.

Quercetin is one other complement for joint well being that has some analysis supporting it, as does fish oil.

In each of those instances, these joint complement substances are thought to exert antioxidant and anti inflammatory results, reducing down on the cellular-level aggravation within the joint.

Q: Is glucosamine in meals?

A: Glucosamine isn’t present in any meals in any important quantity.

It’s a naturally-occurring compound, however you couldn’t get a dose anyplace close to what’s utilized in medical supplementation research even in a really nutritious diet.

The one option to get glucosamine in any important quantity is to make use of a glucosamine complement.

Q: Is there anybody who mustn’t take glucosamine?

A: Since glucosamine is derived from shellfish, you shouldn’t take glucosamine if you understand you could have a shellfish allergy.

Q: Is glucosamine helpful alongside MSM?

A: Glucosamine is assumed to reinforce the organic efficacy of methylsulfonylmethane, or MSM, which is one other frequent complement used for joint ache.

You’ll typically discover each glucosamine and MSM used as substances in joint dietary supplements, and a few analysis has efficiently examined the efficacy of each together (9,10).

Q: What’s glucosamine chondroitin?

A: Glucosamine chondroitin is a time period utilized to joint dietary supplements that embrace each glucosamine and chondroitin, which is a chemically distinct molecule.

Chondroitin is a direct structural element of cartilage, and is assumed to assist enhance the synthesis of recent cartilage in broken joints.

Glucosamine additionally helps assist joint well being, and most multi-ingredient joint dietary supplements financial institution on each glucosamine and chondroitin being more practical together than alone.

Q: How does glucosamine work?

A: Glucosamine is a precursor to a kind of compound known as glycosaminoglycan, which in flip is used each as a constructing block for cartilage, and as a lubricant and shock absorber inside joints.

Analysis on cartilage tissue means that glucosamine will increase cartilage water content material and will increase cartilage protein synthesis, plus boosts the provide of lubricating and shock-absorbing fluids within the joint area.

Q: How lengthy does it take for glucosamine to work?

A: Most analysis on using glucosamine is at the least a number of months in size, so you must strive glucosamine for at the least this lengthy to see if it really works.

One examine on utilizing glucosamine to deal with long-term knee ache explicitly examined the time-course of glucosamine’s results and located that many of the advantages attributable to glucosamine had appeared after eight weeks of use (11).

So, for those who’ve solely been utilizing glucosamine for a few weeks, it’s possible you’ll not have been utilizing it lengthy sufficient to get the complete impact of the complement.

Q: What’s the finest time to take glucosamine?

A: The timing of if you take glucosamine isn’t notably necessary, as a result of it’s pretty long-lasting in your physique.

Nevertheless, you do wish to take it each single day at roughly the identical time to get optimum results.

That’s what the pharmacological analysis helps, and is the protocol utilized by essentially the most profitable analysis research on utilizing glucosamine.

Q: How lengthy does glucosamine keep in your system?

A: Scientific analysis has estimated the elimination half-life of glucosamine at about 15 hours, that means that after taking a full dose of glucosamine, half of it has been eradicated out of your physique 15 hours later (12).

Which means after you cease taking glucosamine, it is going to take a number of days for it to get completely eradicated out of your system.

Due to this comparatively lengthy elimination half life, you don’t should take glucosamine any extra typically than as soon as each day.

Q: What’s glucosamine made out of?

A: Glucosamine is normally made by taking shells from shellfish (like clams or oysters) and breaking down the molecules that make up their shells.

It’s a simple, cheap, and efficient option to purchase a considerable amount of glucosamine.

This course of can also be why it is strongly recommended to take glucosamine when you’ve got a shellfish allergy—it’s probably that the allergens current in shellfish are additionally current in glucosamine in hint quantities.

Associated articles


Glucosamine is a complement whose efficacy has been examined by a number of massive medical trials and has important advantages on joint ache.

Glucosamine seems to be simplest at stopping the lack of cartilage in your joints that comes from osteoarthritis, and likewise appears to be efficient in lots of (however not all) research inspecting ache and day-to-day operate.

This means that glucosamine is finest used early on to decelerate the development of arthritis, when your ache remains to be delicate.

Glucosamine could be very well-tolerated, that means that you simply don’t want to fret about negative effects, and the optimum dosage for finest outcomes seems to be round 1500 mg per day.

For BodyNutrition’s #1 glucosamine advice, click on right here.

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