Rating the most effective probiotic dietary supplements of 2022

Probiotic dietary supplements present a lift to the naturally-occurring useful micro organism that stay inside your physique’s digestive tract. 

Taking a probiotic complement day-after-day is a implausible means to enhance your digestion, enhance your intestine well being, enhance your immune system, and scale back irritation.

Need to discover the most effective probiotics available on the market? Our analysis group put collectively these rankings to search out the cleanest and best probiotic dietary supplements:


1. 1MD Full Probiotics

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For individuals who’re critical about taking essentially the most potent probiotic, 1MD Full Probiotics is the most effective you may get.

No different probiotic complement can compete with the 51 billion cultures and 11 distinctive strains with every serving.

Dr. David Kahana, a famend gastrointestinal physician, says, “When my sufferers ask me what probiotic is finest, I like to recommend 1MD’s Full Probiotics Platinum. Full Probiotics Platinum has 11 completely different strains and ensures 50 billion stay cultures per capsule. It additionally accommodates an efficient dosage of Nutraflora prebiotic fiber that may guarantee these cultures get the gasoline they should actually make a distinction in your intestine.”

Why is that this necessary?

As a result of a number of probiotic merchandise solely have 2-3 completely different strains, and consuming probiotics with a various collective of fine micro organism strains provides a greater bacterial stability in your intestine.

From total immune well being to offering your physique with higher digestion and intestine well being, 1MD Full Probiotics is among the higher day by day habits you possibly can have within the complement area.

All pure, no synthetic sweeteners, no synthetic coloring, no synthetic preservatives and 100% GMO-free.

That is necessary. If you’re taking a probiotic as a day by day complement, the very last thing you need is “added stuff” to mess along with your fatigue, oxidation, blood stress and microbiome stability.

Made within the USA and in an FDA-approved facility.

BodyNutrition‘s all-around probiotic complement winner of 2021.

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2. Probiotic 40 Intestine Enhance +

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Nuzena is a brand-new complement firm recognized for his or her potent formulation.

Probiotic 40 Intestine Enhance + by Nuzena is shamelessly stacked and in addition one of many cheaper choices on the checklist.

They’re additionally some of the sturdy probiotic formulation that we’ve reviewed. The components accommodates 40 Billion probiotic micro organism made up of 4 particular person strands for elevated bioavailability.

With regards to intestine well being we all know that having a number of strands of probiotic micro organism your dietary supplements is crucial — as discovering the right match to your mitochondria can differ between completely different strands.

Whereas a number of the different probiotic dietary supplements we’ve reviewed right here have comparable strands, Nuzena actually stands out with the standard of their components.

3. NOW Probiotic-10

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Though this falls in need of our winner, NOW Probiotic-10 accommodates ten completely different probiotic micro organism strains, which whole to an eye-popping 25 billion colony forming models. 

The micro organism are delivered by way of a vegetarian capsule, and NOW Probiotic-10 makes use of commonplace “unbranded” micro organism strains, which each saves you cash and ensures that you’re getting the identical particular strains which are utilized in scientific research on the advantages of probiotics. 

With a easy cellulose capsule, a number of the micro organism could be misplaced to abdomen acid, however the enormous total micro organism rely ought to greater than make up for this.

4. Backyard of Life Primal Protection Extremely

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Backyard of Life all the time has an attention-grabbing tackle dietary supplements, and their Primal Protection Extremely probiotic is not any exception. The 13 strains of probiotic micro organism are supported by a matrix of natural oat grass processed with an enzymatic process to assist micro organism development, in addition to a small quantity of iron, which is understood to massively enhance micro organism development contained in the physique. 

In addition they embrace “ionic plant based mostly minerals,” presumably to spice up development additional. Backyard of Life usually has a find it irresistible or hate it method; if you need all of the extras, it’s an excellent selection, however should you simply need plain outdated micro organism in a capsule, there are higher choices.

5. Vitamin Necessities Probiotic

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In order for you a “micro organism bomb,” look no additional: Vitamin Necessities crams some 15 billion colony forming models into their tablets, together with half a gram of “pre-biotic” supplies that foster the expansion and replica of the micro organism. Vitamin necessities is completely different from a few of its opponents in that it’s comprised of only one probiotic micro organism, bacillus coagulans. 

Luckily, this is among the better-researched probiotics, with analysis up to now discovering that it’s a secure and efficient remedy for irritable bowel syndrome and associated gastrointestinal issues (1). The pill is a reasonably easy one, fabricated from calcium carbonate, cellulose, and stearic acid, so it might face some issues getting the majority of the probiotic micro organism into your intestines, however the excessive variety of micro organism colony forming models to start with ought to assist offset that downside.

6. Hyperbiotics PRO-15

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Hyperbiotics makes use of a formulation that packs fifteen completely different micro organism strains into their proprietary mix with a complete of 5 billion CFUs.

Hyperbiotics additionally employs a proprietary “pearl capsule” expertise which is meant to permit extra of the micro organism to make it to your intestines to populate the intestine flora. With Hyperbiotics’ allergen-free assure, this product is an enormous winner.

7. Nature’s Bounty Extremely Probiotic 10

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The ever-present and trusted Nature’s Bounty model delivers relating to probiotics. Their Probiotic 10 complement accommodates 20 billion colony forming models and, because the title suggests, ten completely different strains of micro organism. 

The capsules are vegetarian, and there aren’t any extraneous substances included both, so this one’s a really stable selection.

8. Bio Schwartz Superior Power Probiotic

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Although Bio Schwartz consists of an enormous quantity of micro organism (40 billion colony forming models!) the alternatives of which of them to incorporate are somewhat odd.

The staple micro organism lactobacillus acidophilus is there, however the different three are much less widespread and fewer well-researched micro organism. The complement additionally consists of fructooligosaccharides to assist the expansion of the micro organism, but it surely doesn’t doc how a lot it really consists of within the complement.

9. Dr. Tobias Deep Immune Probiotics

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The probiotic mix supplied by Dr. Tobias consists of 5 several types of micro organism which whole to a bit underneath 5 billion colony-forming models. 

The capsules are one other main promoting level; Dr. Tobias claims that their capsules resist the digestion of the abdomen acid, making it in order that extra micro organism make their means into the intestinal tract as a substitute of being destroyed by abdomen acid.

10. Herrmann Well being Merchandise Superior Probiotic

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With a mixture of seven completely different probiotic micro organism, together with Lactobacillus, Bifidobacterium, and Bacillus strains, Hermann Well being Merchandise provides a stable combo of wholesome micro organism, although solely at a dose of 5.75 billion CFUs. 

Class winners

Finest probiotics total: 1MD Full Probiotics

1MD takes our prime spot due to its unbeatable probiotic rely–at 50 billion CFUs and 11 distinctive bacterial strains, it stands head and shoulders above the competitors relating to selection and efficiency. Add to that some fructo-oligosaccharides for prebiotic assist and also you’ve obtained a transparent winner. 

Finest probiotics with lactobacillus micro organism: Nuzena Probiotic 40 Intestine Enhance +

Lactobacillus micro organism are a class of probiotic micro organism that break down carbohydrates and are significantly in style to take for digestive well being. With regards to probiotics that present lactobacillus, Nuzena Probiotic 40 Intestine Enhance + is our favourite due to its potent combo of three completely different strains of lactobacillus micro organism. 

Finest probiotics for ladies: 1MD Full Probiotics

1MD is our prime choose for ladies due to its numerous vary of probiotic strains. Girls have larger charges of digestive well being issues like IBS and constipation than males, so making certain a broad vary of wholesome intestine micro organism is especially necessary for ladies. Since 1MD tops the charts relating to selection, it’s our prime choose for ladies. 

Finest probiotics for weight reduction: Nuzena Probiotic 40 Intestine Enhance +

With regards to weight reduction, Nuzena is our choose due to its concentrate on delivering a excessive CFU rely of essentially the most well-studied micro organism that contribute to intestine well being. Its use of particular, well-studied lactobacillus and bifidobacterium strains makes it our favourite for individuals trying to shed extra pounds. 

Finest probiotic and prebiotic mixture: Backyard of Life Primal Protection Extremely

Backyard of Life makes use of a mixture of enzymatically-processed oat grass and barley grass to offer a matrix of fiber and vitamins that assist wholesome intestine bacterial development. In order for you a stable dose of wholesome micro organism plus an all-natural supply of prebiotic vitamins, Backyard of Life is the way in which to go. 

Finest probiotics for digestive well being: 1MD Full Probiotics

Whether or not you might have digestive issues like irritable bowel syndrome or are simply trying to enhance your digestive wellness, 1MD is a superb selection. It has a excessive dose of a number of completely different wholesome intestine micro organism strains, and consists of prebiotic vitamins as effectively to make sure these micro organism proceed to develop and multiply. 

Who can purchase probiotics?

Probiotics are most necessary for individuals who might have a disrupted or poor intestine microbiome. Probiotics are generally beneficial following a course of antibiotics, for instance.

Whereas antibiotic medicine could be very efficient in opposition to infectious micro organism, additionally they lay waste to the wholesome micro organism current in your abdomen and intestines, paradoxically leaving you weak to well being disruptions sooner or later.

Taking a probiotic complement after a course of antibiotics will help rectify this imbalance. Probiotics are additionally very useful in many individuals who’ve intestinal issues like Crohn’s illness, ulcerative colitis, or irritable bowel syndrome (IBS).

The mechanisms behind many of those intestinal issues are unknown, however seem like linked each to your immune system operate and your ranges of probiotic micro organism.

Not solely are intestine micro organism populations completely different between individuals with intestinal issues and well being individuals, however modifying the intestine micro organism in individuals with irritable bowel syndrome or Crohn’s illness can result in enhancements in signs, which strongly suggests intestine micro organism is linked to the issue.

Past individuals with these well being issues, there may be rising recognition that even wholesome individuals can have a disrupted intestine biome on account of their eating regimen.

Western diets, with their comparatively low fiber content material and excessive ranges of sugar and refined carbohydrates, don’t promote the sort of sturdy and numerous intestine biome that you simply’d get on a eating regimen excessive in fiber, recent fruits, and greens.

Some (although not all) researchers even recommend that youngsters may profit significantly from a probiotic complement. One article in Present Opinions in Pediatrics argues that, because of the sturdy circumstantial proof connecting a wholesome intestine micro organism inhabitants with decreased dangers for bronchial asthma, allergic reactions, and even sort 2 diabetes and weight problems, pediatricians ought to contemplate probiotic supplementation for kids.

Even wholesome adults are more and more turning to probiotics to higher their odds in opposition to these identical continual ailments, due to the circumstantial proof that’s regularly piling up that signifies that intestine micro organism composition is among the cornerstones to total well being and wellness.

How we ranked

We began by aggregating the entire newest, hottest, and best-selling probiotic dietary supplements. Amongst these probiotics, we particularly seemed for the dietary supplements that had a stable dosage of probiotics.

Not like different dietary supplements, probiotics don’t measure doses in milligrams or IUs: they use a particular unit referred to as colony forming models, or CFUs for brief.

These colony forming models are outlined by their capability to begin a bacterial colony, or development of micro organism. The extra CFUs, the extra stay micro organism are contained within the complement.

Medical analysis signifies that you really want at the least one to 5 billion CFUs per day minimal to get the specified results, so we dumped something that had lower than one billion CFUs, or that didn’t explicitly state its stay bacterial colony content material.

Secondly, we prioritized dietary supplements that had larger doses. That’s why 1MD and Now Probiotic-10 rose to the highest: their ultra-high doses of fifty and 25 CFUs made them prime contenders, and on par with a number of the strongest probiotic dietary supplements which have been examined in medical analysis.

Subsequent, we sought out manufacturers that used particular strains of useful micro organism versus common classes or species.

For instance, regardless of its recognition, NewRythm Probiotics didn’t make our checklist for that reason: it merely lists the species of micro organism, similar to lactobacillus acidophilus.

Examine that to Nature’s Bounty Probiotic 10, which lists the precise pressure of micro organism used, similar to Lactobacillus plantarum 299v. This degree of specificity allowed us to check the substances to what has been examined and confirmed useful within the scientific literature.

Lastly, we prioritized probiotic dietary supplements that offered a wide range of probiotic strains recognized to be useful.

Manufacturers that centered solely on one sort of probiotic, similar to Klaire Labs Ther-Biotic Issue 4, didn’t make the minimize since we have been in search of a various vary of confirmed probiotic micro organism, not only one sort.

Among the particular sort of probiotic micro organism we seemed for embrace lactobacillus, bifidobacterium, and streptococcus thermophilus—all of those probiotics have been particularly investigated for his or her well being advantages in scientific analysis.

When attainable, we matched up particular bacterial strains in business probiotics with the strains utilized in analysis to make sure the top-ranked probiotic dietary supplements have been the best ones available on the market.


Probiotics will help you shed extra pounds, bump up immune operate, enhance your digestion, and even minimize your danger of continual ailments.The significance of getting a wholesome intestine doesn’t all the time get the eye it deserves, however analysis signifies it’s simply as important as meals selections, good sleep and train (1, 2).

We have now ten instances as many micro organism in our our bodies as we do cells, and most of them stay within the intestine.

When these microorganisms are comfortable, we get pleasure from well being advantages; when bacterial colonies aren’t thriving, we might endure a variety of detrimental results. (3)

Sure sorts of yeast can even act as probiotics, however a lot of the conditioning required for preserving the intestine wholesome is carried out by colonies of micro organism.

Probiotics could be taken in complement kind, and may additionally be ingested by consuming probiotic meals ready via fermentation processes that encourage the expansion of pleasant micro organism. Some in style fermented meals embrace kefir, kimchee, sauerkraut, tempeh and yogurt.

You may additionally be accustomed to prebiotics, that are fibers that truly feed pleasant intestine micro organism. (4)

Bacterial communities work to take care of the integrity of intestine wall. The intestine wall is important in stopping substances within the colon from leaking into different components of the physique and stimulating an immune response. (5, 6, 7)

Moreover pleasant micro organism, dangerous intestine flora additionally exist, and when the stability will get out of whack, it might result in ailments like sort 2 diabetes, metabolic syndrome, coronary heart illness, melancholy, Alzheimer’s illness, colorectal most cancers and lots of extra. (8, 9, 10)

That is the world the place essentially the most analysis has been completed on probiotics, particularly in regard to diarrhea related to taking antibiotics. (11)

Diarrhea usually happens after a course of antibiotics is taken to deal with a medical situation, and might persist for lengthy durations of time. Antibiotics eradicate many micro organism within the intestine, and this will shift the stability so dangerous micro organism dominate and thrive.

Many research point out probiotics can remedy this downside (12, 13), in addition to being efficient in decreasing bloating, gasoline, constipation, and different intestinal issues, together with signs related to irritable bowel syndrome (IBS). (14, 15)

Probiotics can help in treating ulcerative colitis and Crohn’s illness , and may additionally assist combat helicobactor pylori infections. These infections are attributable to the micro organism that results in ulcers and raises the chance of abdomen most cancers. (16,17)

Anybody who has digestive points which have been tough to resolve may contemplate taking a probiotic complement.

Probiotic micro organism may even make it easier to shed extra pounds. For those who’re carrying round a big quantity of additional weight, chances are high your intestine flora are completely different than somebody who’s skinny or of regular weight. (15)

Researchers enjoying with this idea transplanted intestine flora from skinny animals into overweight animals, and the consequence was dramatic: fats animals started to shed extra pounds. (16)

Human research point out that having the suitable intestine flora will help with weight management. (17, 18)

Information from a examine carried out in 2013 with greater than 200 individuals affected by central weight problems (massive quantities of stomach fats) supplied encouraging outcomes: over three months, members taking the probiotic lactobacillus gasseri had a mean lower of 8.5% in stomach fats mass. (19)

It took solely a month for check topics to realize again the stomach fats they misplaced after they stopped taking the probiotic.

One other examine indicated that Bifidobacterium and lactobacillus ramnosis might assist in stopping weight problems and supporting weight reduction. (20)

Potential well being advantages ensuing from these results might embrace a decreased danger of creating continual Western ailments like autoimmune ailments, psychological issues, arthritis and coronary heart illness. Additional analysis is prone to reveal much more well being benefits related to wholesome intestine flora.

The usage of probiotics has been related to enhancements in a variety of different well being situations, together with dropping blood stress for sufferers with hypertension, decreasing irritation (21), enhancing immune system operate (22), decreasing ldl cholesterol and LDL ldl cholesterol, bettering pores and skin situations similar to rosacea, zits and eczema (23) and decreasing signs in sufferers affected by melancholy and nervousness (handled with these strains: bifidobacterium longum and lactobacillus helveticus) .

Uncomfortable side effects

Taking probiotics is totally secure for most individuals, although some expertise digestive unwanted effects in the course of the first few days; stomach discomfort, bloating and gasoline are the most typical issues. (24) Improved digestion often follows these preliminary signs.

These with compromised immune methods, similar to sufferers identified with AIDS or HIV, have had points with an infection after taking probiotics, and anybody with a medical situation ought to discuss with a health care provider earlier than making a call about supplementing. (25)

For those who’re trying to deal with a selected well being difficulty, it’s necessary to do your homework and discover out which strains of probiotics have been profitable in particular functions; all the time buy probiotics from a trusted producer.

Really helpful dosage

Probiotic micro organism have been researched intensively in the previous few years, and we now have rather more detailed info on the suitable dosage for a probiotic complement (although there’s nonetheless loads of work to be completed on the scientific entrance).

For starters, nearly no medical research have demonstrated efficacy with probiotic doses of lower than one billion CFUs, and most use at the least 5 billion CFUs per day. Past this, the image will get somewhat murky as a result of the suitable dose appears to rely upon the precise well being situation that’s being handled.

For example, one examine on utilizing probiotics to enhance immune operate in older adults discovered that 5 billion CFUs per day was equally efficient in comparison with a dosage of fifty billion CFUs per day (38).

However, a evaluation article highlighted a powerful dose-response relationship in utilizing probiotics to deal with diarrhea that happens after taking antibiotics (39). In these circumstances, doses of over 100 billion CFUs per day have been definitievely more practical than decrease doses.

The takeaway from this analysis is {that a} baseline dosage of 5 billion CFUs per day is an efficient place to begin, however for some situations—significantly these linked to the digestive tract—a lot larger doses, within the vary of 50-100 CFUs per day, could be a good suggestion.


Q: What are probiotics?

A: Probiotics aren’t simply any sort of micro organism—they’re good micro organism that stay in your gut and which have been related to constructive well being advantages.

Usually, these micro organism are present in fermented meals, just like the lactobacillus and bifidobacterium present in cheese and yogurt. To get probiotic micro organism in larger doses, a probiotic complement is the way in which to go.

Q: Can a probiotic complement work as a thermogenic for weight reduction?

A: The connection between intestine micro organism and weight reduction is complicated, however clearly related: overweight individuals have considerably completely different intestine micro organism profiles in comparison with wholesome individuals, even after controlling for issues like dietary consumption.

However, the agricultural business has lengthy used particular bacterial strains to induce weight acquire in cattle and different inventory animals.

The load loss or weight acquire results of a probiotic relies on the precise pressure getting used; some analysis means that sure strains of probiotics will devour a number of the energy that you simply eat, which might (in principle) forestall weight acquire.

Nonetheless, in case you are obese or overweight, sure probiotics do produce other advantages, similar to doubtlessly having the ability to scale back your danger for sort 2 diabetes, even impartial of any weight reduction that will happen.

Q: What do probiotics do?

A: As soon as inside your digestive tract, the bacterial spores within the colony forming models begin multiplying. After all, they don’t multiply perpetually, as a result of they must coexist in an ecosystem of different micro organism in your abdomen and intestines which have entry to a restricted quantity of meals.

Nonetheless, they do have an enduring impact on the composition of your intestine micro organism. These modifications could be particularly useful to jump-start the advantages of a nutritious diet: scientific analysis means that, whereas your eating regimen is by far the most important determinant of your intestine biome, short-term dietary modifications have little impact on intestine micro organism composition (40).

To spice up the useful modifications in intestine micro organism composition, a probiotic complement could possibly be simply the trick.

Q: How lengthy does it take for probiotics to work?

A: Medical analysis suggests that you simply want at the least eight to 9 weeks, and maybe as much as 12 weeks, for probiotics to have a statistically detectable impact.

That being mentioned, chances are you’ll begin to really feel the advantages of probiotics a lot sooner, since these medical research must detect the impact amongst massive populations with plenty of inter-individual variability.

Nonetheless, probiotics do take time to have an impact—don’t anticipate wonderful outcomes in a single day. At the very least eight weeks is critical to evaluate whether or not your probiotic complement is having a measurable impact in your intestine micro organism.

Q: What’s the distinction between prebiotics and probiotics?

A: Probiotics, as described earlier, are dwelling bacterial cells that reproduce inside your physique and definitively change the make-up of your intestine micro organism.

There are various completely different sorts of probiotic micro organism, however all of them share the truth that they’re, essentially, dwelling creatures that multiply inside your physique.

Conversely, prebiotics are like purposeful meals for micro organism: prebiotics are vitamins that facilitate the expansion of useful micro organism inside your digestive tract.

Even one thing so simple as psyllium husk or different kinds of fiber dietary supplements could be a prebiotic, as a result of probiotic micro organism can devour this fiber for vitality. Likewise, you’ll additionally see prebiotics that comprise inulin, a plant-derived fiber that’s extremely helpful as vitality for probiotic micro organism, in addition to fructooligosaccharides, that are carbohydrates equally helpful for probiotic micro organism.

Prebiotics are sometimes used as a “booster” to both increase your pure ranges of probiotic micro organism, or together with a probiotic complement to speed up the expansion of the probiotics that you’re taking.

You’ll discover prebiotic substances in a number of of our top-ranked probiotic dietary supplements, and we’ve additionally particularly ranked and reviewed the finest prebiotic dietary supplements individually.

Q: How must you take probiotics and antibiotics on the identical time?

A: Although it sounds counterintuitive, the scientific literature means that taking probiotics on the identical time as antibiotics is the easiest way to stop a number of the the detrimental unwanted effects of an antibiotic.

After all, as with all prescription medicine, it’s best to discuss to your physician to verify there aren’t any particular causes to not combine prebiotics and probiotics, however massive meta-analysis research of medical analysis has discovered that probiotic dietary supplements are extraordinarily efficient at stopping unwanted effects like diarrhea, however may not be as useful should you wait till unwanted effects have already developed (41).

In different phrases, they’re a greater prevention than remedy. In medical analysis, probiotics and antibiotics are often taken on the identical time: the probiotic micro organism appear resilient sufficient to not get completely destroyed by the antibiotics. Remember that not all antibiotics work on all micro organism, so a broad-spectrum probiotic complement might have a greater probability of surviving in the course of the course of an antibiotic remedy.

Whereas widespread sense may point out that it might be wasteful to take probiotics and antibiotics on the identical time, the scientific analysis really suggests exactly the alternative: it’s higher to begin taking probiotics immediately as a substitute of ready to complete your course of antibiotics.

Associated articles


Probiotics are dietary supplements that comprise useful micro organism that enhance the well being of your digestive system and enhance your immune operate.

They supply help to your physique for cultivating pleasant intestine micro organism, which could be useful in bettering a variety of well being situations, together with immune system operate, weight administration, melancholy and systemic irritation.

Shoot for a dosage of at the least 5 billion CFUs per day, and better in case you are particularly taking probiotics for a digestive tract difficulty.

If you’re taking probiotics to assist forestall unwanted effects from a course of antibiotics, don’t delay taking a probiotic complement till you might be completed along with your antibiotic prescription—the scientific analysis reveals that taking them on the identical time is definitely far more practical than ready till digestive unwanted effects from antibiotics seem.

Whereas there may be nonetheless lots extra analysis to do on probiotics, the outcomes to this point are already very promising.

For BodyNutrition‘s #1 probiotic complement advice, click on right here.

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